Miruvor

GLP-1 drugs (semaglutide, tirzepatide)

3 people describe trying GLP-1 drugs (semaglutide, tirzepatide) (1 with ME/CFS, 2 with long COVID).

33%
recovered fully or nearly
1 of 3
67%
improved (substantial or partial)
2 of 3
0%
relapsed
0 of 3
0%
no benefit
0 of 3

How it went

Did it last?

  • No one said the benefit wore off.
  • No one said they needed to keep it up to stay well.

Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.

Outcome describedAccountsShare
Full recovery133%
Near-full00%
Substantial133%
Partial133%
Relapsed00%
No benefit00%

Only 3 accounts. Treat these percentages as anecdotes, not rates.

By how ill people were

Severity at worstHow it wentnRecovered
Very severe10%

2 accounts don’t say how ill the person was.

How often it comes up

Posts that mention GLP-1 drugs (semaglutide, tirzepatide), per 1,000 posts each year. Hover a point for the count.

05102009201220152018202120242026
Show as a table
YearPosts mentioning itAll postsPer 1,000
200901840.0
201006820.0
201107040.0
201201,4910.0
201301,9950.0
201402,7070.0
201502,5660.0
201612,0230.5
201703,3810.0
201802,5230.0
201901,6370.0
202003,3180.0
202102,4690.0
202201,8710.0
202302,3620.0
202412,1760.5
2025141,34910.4
2026 (so far)58995.6

Posts in the forum threads and blog comments we archived, 34,337 in all, counted per year. A mention means the post names the treatment, not that the writer took it. These pages all contain a recovery story, so they show what those communities discussed, not everyone with ME/CFS or long COVID. All trends

All 3 accounts

  • Experimental peptides are being advertised for Long COVID (Joshua)

    Partial Long COVID thesicktimes.org Jul 2026

    Joshua began microdosing tirzepatide about six months before the article was written, though no specific dose is given. The article does not describe how long he had been sick or how severe his Long COVID was, but he reported that within hours of his first…

  • ME/CFS patient substantially improved with spironolactone 100 mg daily

    Full recovery ME/CFS forums.phoenixrising.me Apr 2026

    Poster combined spironolactone 25mg/day with LDN, a GLP-1 agonist and NP thyroid and states plainly "My CFS is cured, yes cured...my health is amazing," while noting he still needs cortisol supplementation. Because several drugs were changed together it is…

  • Scripps launches digital clinical trial to test repurposed drug for Long COVID

    Substantial Long COVID Very severeIll 1 year forums.phoenixrising.me Oct 2025

    Credits GLP 1. An unnamed patient was ill 1y with very-severe long COVID and reports a substantial improvement. Poster's daughter, bedridden a year, thriving days after Ozempic.