Miruvor
ME/CFS Very severe → relapsedBenefit faded or relapsed

Dramatic improvement in mental symptoms from melatonin dosed in the DAY

Condition
ME/CFS
At worst
Very severe (bedbound, unable to do basic care)
Ill for
Not stated
Published
Mar 2016

Summary

douglasmich reports daytime melatonin cut his usually "crippling" brain fog by about 80%, eliminated suicidal thoughts for that day, and briefly restored joint stability and enjoyment of music. He is explicit that the benefit is only a single day long, followed by a "HUGE CRASH" with return of symptoms, so this reads as a striking but non-durable daily on/off effect rather than a lasting improvement.

Read it in their words

forums.phoenixrising.me

Symptoms mentioned

Symptoms: Brain fog.